Pharmaceutical Formulation & Dosage Form

7. Adding a water-miscible solvent such as ethanol or glycerin to dissolve a poorly water-soluble drug
8. Total number of tablets tested when the first disintegration stage is borderline and 12 more are added
9. Injection route into muscle that permits the larger volume, up to about 3 mL, versus the smaller subcutaneous limit
11. Factor, ten-fold here, that you multiply by to recover the true drug concentration in the dissolution vessel
12. One of the three percutaneous routes, passing directly through the skin cells (corneocytes)
14. Type of effect a transdermal patch is designed to produce, unlike a topical product that acts only where applied
15. Two-phase oil-and-water system. For very dry skin the water-in-oil type gives the longest-lasting moisturisation

1. Suspension state where particles form loose aggregates that settle fast but redisperse with a gentle shake
2. Amphiphilic agent that lowers tension at the oil/water boundary and forms a film around droplets to stabilise an emulsion
3. Spectrophotometric reading fed into a standard curve to calculate a sample's concentration
4. Compendial test timing how long a tablet takes to break apart in fluid
5. Sterilisation by passing a solution through a 0.22 micron membrane, the method of choice for a heat-sensitive injectable
6. Sweetened, clear, hydroalcoholic oral liquid, sitting between a sugary syrup and a more concentrated tincture
10. Test ensuring every dosage unit holds a consistent amount of active drug within set limits
13. Volatile alcohol used as a chemical penetration enhancer that increases a drug's partitioning into the stratum corneum