Pathophysiology, Clinical Manifestations & New Diagnostic Criteria

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Across
  1. 3. excess male pattern terminal hair growth
  2. 6. Elevated insulin state that increases GnRH, driving excess ovarian androgen production
  3. 8. Primary site of excess androgen production in PMOS
  4. 9. acknowledging insulin resistance, obesity, risk for type 2 DM, and cardiovascular disease
  5. 10. Third hormonal acis disrupted in PMOS alongside insulin and androgens
Down
  1. 1. Hormone is now included in the updated PMOS diagnostic criteria as an alternative to ovarian morphology
  2. 2. failure to release a mature egg, underlies infertility and endometrial cancer in PMOS
  3. 4. Diagnostic framework in PMOS
  4. 5. fewer than 9 menstrual cycles per year
  5. 7. decreased levels in PMOS, resulting in elevated free testosterone