12.1

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Across
  1. 1. (+)chromogranin, (-)keratin
  2. 3. indicative of neuronal or neuroendocrine differentiation
  3. 7. skeletal muscle malignancy,(+) desmin
  4. 8. used in microwave antigen retrieval with a pH of 8 or 10
  5. 9. cells that produce hCG
  6. 12. highly sensitive marker for epithelial cells
  7. 14. (+)actin, desmin, myoglobin
  8. 15. enzyme for proteolytic digestion
Down
  1. 2. positive in teratomas
  2. 4. CNS glial cell that expresses GFAP
  3. 5. type of antigen retrieval that provides more consistent antigen recovery
  4. 6. type of antibody derived from several plasma cell lineages
  5. 10. expresses CD15 and CD30
  6. 11. always positive in Schwanommas
  7. 13. technique in producing monoclonal antibodies
  8. 14. laboratory animal used in monoclonal antibody production