CROSSWORD

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Across
  1. 1. Telomeric DNA (ALT) form used as diagnostic marker. Shape. (6)
  2. 5. Catastrophic event of fragmentation and reordering of chromatin (14)
  3. 7. Hallmark of cancer suggesting self renewal potential (8)
  4. 8. Specialised dynamic region where cancer cells thrive (5)
  5. 9. Extracts of periwinkle flower, anti-tubulin activity. Genus. (5)
  6. 11. ‘To gnaw’- CAR T cells extract and acquire tumor antigens by this process (12)
  7. 12. Non-random, positively selected mutations in mtDNA contributing to oncogenic process (6)
Down
  1. 2. Viral propogation without integration in host DNA, characteristic Epstein Barr Virus (7)
  2. 3. Apoptosis following contact loss with extracellular matrix (7)
  3. 4. Specific mucin-rich ovarian tumor metastasised from primary stomach cancer.noun. (10)
  4. 5. Loss of this protein enhances migratory potential of cells (8)
  5. 6. Monoclonal Ab targetting a receptor tyrosine kinase protein of EGF family in breast cancer (9)
  6. 7. Protein promoting Darwin's principle in context of cancer (8)
  7. 10. Phenomenon of shielded propogation by enucleated cells for metastasis (8)