OCR Biotechnology

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Across
  1. 3. Compounds produced after growth slows, e.g., antibiotics
  2. 4. Uptake of foreign DNA by bacteria
  3. 5. Strong chemical linking of enzymes to supports
  4. 7. Using organisms or enzymes to make useful products
  5. 9. Organism containing DNA from another species
  6. 10. Carrier used to transfer DNA into a cell
  7. 14. Closed-culture method with no added nutrients
  8. 17. Enzymes fixed to an inert support
  9. 18. Molecules made during normal growth phase
  10. 19. Using GM organisms to produce medical substances
  11. 22. Open-culture system with fresh medium supplied
  12. 24. Phase where microorganisms die faster than they divide
  13. 25. Microbial process used to produce substances in industry
  14. 26. Period of rapid microbial reproduction
  15. 28. Technique used to amplify DNA sequences
  16. 29. Enclosing enzymes in semi‑permeable membranes
  17. 30. Methods to prevent contamination of cultures
Down
  1. 1. Method to separate DNA fragments by size
  2. 2. Making multiple identical copies of a gene
  3. 6. Growing cells or tissues outside the organism
  4. 8. Enzymes secreted outside cells
  5. 11. enzymes Enzymes that act within cells
  6. 12. Small circular bacterial DNA used in genetic engineering
  7. 13. Growth period where cell division equals cell death
  8. 15. Using organisms to remove pollutants from environments
  9. 16. Enzyme that joins DNA fragments together
  10. 20. DNA formed by joining sequences from different sources
  11. 21. Immobilising enzymes within a gel matrix
  12. 23. Proteins that cut DNA at specific sequences
  13. 27. Initial period of microbial growth with little division