Week 8 PASS - Transcription in Prokaryotes and Eukaryotes

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Across
  1. 3. Non-coding sequence removed during RNA processing
  2. 5. Initial promoter-binding stage where DNA remains double stranded
  3. 8. CA-rich sequence recognised by rho helicase during rho-dependent termination
  4. 9. Protein that replaces sigma during elongation and assists with termination
  5. 10. DNA strand used by RNA polymerase to synthesise complementary RNA
  6. 13. Addition of adenine nucleotides to the 3’ end of eukaryotic mRNA
  7. 14. Transcription phase involving RNA synthesis in the 5’ to 3’ direction
Down
  1. 1. Stage where sigma dissociates after approximately 8–9 nucleotides are synthesised
  2. 2. Enzyme that cleaves pre-mRNA downstream of the AAUAAA signal
  3. 4. Process requiring selective gene expression in different cell types
  4. 6. Complete bacterial RNA polymerase complex containing the sigma factor required for promoter recognition
  5. 7. Large RNA-protein complex responsible for removing introns from pre-mRNA
  6. 11. Secondary RNA structure formed by self-complementary base pairing during intrinsic termination
  7. 12. Loop-like intermediate formed during intron removal