299 Catagory 2 Assignment 3

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Across
  1. 2. Illness s/s include fever, fatigue, loss of appetite, lethargy, anemia, leukopenia, hemorrhage, infection, electrolyte imbalances, emaciation.
  2. 3. stochastic effects includes cancer, genetic effects
  3. 6. risk model predicts that a specific number of cancers will occur as a result of exposure.
  4. 7. 50/30 signifies the whole-body dose of radiation that can be lethal to 50% of exposed population within 30 days
  5. 8. of ARS Hematopoietic syndrome, gastrointestinal syndrome, cerebrovascular syndrome.
  6. 10. effects biologic effects of ionizing radiation on future generations due to irradiation of germ cells in previous generations.
  7. 11. effects long term results of radiation exposure
  8. 12. Syndrome- 50+ Gray, death occurs. Damaged blood vessels and permeable capillaries permit fluid to leak into the brain, causing increased ICP.
  9. 14. deterministic Somatic Effects-Includes cataract formation, fibrosis, organ atrophy, loss of parenchymal cells, reduced fertility, sterility
  10. 15. stages Prodromal, latent period, manifest illness, death or recovery.
  11. 17. effects damage to non-reproductive cells, may be early or late effects. Self.
  12. 18. Period may last 5 days- 4 weeks. No symptoms are visualized. “False calm”
  13. 20. Syndrome appears at a threshold of 6-10 Gy and peaks after a dose of 10Gy. Death occurs in 3-5 days due to catastrophic damage to the epithelial cells that line the GI tract, fluid loss, or dehydration. Can be prolonged with medical support to 3-10 days.
  14. 21. the production or origin of cancer.
Down
  1. 1. aka non-random, threshold
  2. 4. Radiation Syndrome(ARS, radiation sickness) early somatic tissue reactions, occurring in humans soon after whole body reception of large doses of ionizing radiation delivered over a short period
  3. 5. curve (DR curve) goal is to establish relationships between radiation and dose response.
  4. 7. threshold (LT)- biologic response does not occur below this dose
  5. 9. Syndrome aka bone marrow syndrome- occurs when people receive whole-body doses of ionizing radiation from 1-10 Gray. Causes the number of RBC, WBC, and platelets in circulating blood to decrease. Body becomes more susceptible to infection and to hemorrhage. Death occurs in 6-8 weeks in some who receive a whole body dose of 2 Gray, larger doses will cause death sooner. If a sublethal dose of 1-2 Gray pt may recover in 3-6 weeks.
  6. 13. risk model predicts the number of excess cancers will increase as the natural incidences increases with advancing age. Predicts a percentage increase rather than a specific number.
  7. 16. aka random, probabilistic, non-deterministic, non-threshold
  8. 17. Threshold-High dose response in radiation therapy
  9. 18. non threshold (LNT) response to radiation is directly proportional to the dose of radiation
  10. 19. A few hours after irradiation, severe N/V/D persists 24 hrs
  11. 22. effects- occur soon after humans receive large doses of irradiation