5000 module 1B

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Across
  1. 2. Fetal hypoxia results in a release of catecholamines and norepinephrine, causing vasoconstriction and fetal hypertension, which may result in cardiac remodeling or hypertrophy of the ___ ____, which increases the risk of RDS after birth (2 words).
  2. 4. This condition, marked by hormone imbalances and irregular periods, can increase the risk of gestational hypertension and gestational diabetes (acronym).
  3. 8. Preeclampsia can result in elevated serum creatinine with a decreased ____ (acronym).
  4. 9. Preeclampsia with liver damage; occurs due to placental hypxoia resulting in dead placental fragments entering the maternal bloodstream and causing inflammation of the microvasculature of the liver (acronym).
  5. 11. Limited exposure to this is thought to be a risk factor for preeclampsia, due to the immune system attacking foreign DNA; may be why IVF and nulliparous individuals are at an increased risk.
  6. 12. Upregulation of this hormonal process due to a hypoxic placenta can contribute to preeclampsia by increasing maternal blood pressure (acronym).
  7. 13. Infants born to mothers with diabetes have an increased risk of this, due to a risk for polycythemia and interference with maternal milk production.
  8. 14. ____ injury of maternal blood vessels causes intravascular inflammation and platelet and thrombin activation, contributing to preeclampsia.
  9. 15. Preeclampsia may cause shortness of breath and chest pain due to pulmonary ____ from hypertension.
  10. 16. Gestational diabetes may result in ____, which can increase the risk of preterm delivery, neonatal hypoglycemia, jaundice, respiratory distress syndrome, and perinatal mortality.
  11. 18. GHTN may result in ___ delivery due to placental abruption or iatrogenically induced labour if the risks of carrying to term are deemed greater than the benefits.
  12. 20. Part of "HELLP;" damaged hepatocytes release cellular enzymes, causing nausea and vomiting (3 words).
  13. 23. The presence of this in the urine indicates damage to the kidney filtration membrane; clinical indicator of preeclampsia.
  14. 24. Incomplete transformation of these arteries which invade the endometrium during embryo implantation may result in oxidative stress from hypoxic placental development, increasing the risk of preeclampsia.
  15. 26. Medication which may be given to hypertensive pregnant patients to increase the seizure threshold, reducing the risk of eclampsia; increases the risk of post-partum hemorrhage (2 words).
Down
  1. 1. Part of "HELLP;" shearing of RBCs as they pass through occluded capillaries, resulting in multi-organ damage.
  2. 3. Infants born to mothers with diabetes have an increased risk for this, due to maternal hypomagnesemia from diuresis.
  3. 5. Hormone produced by the placenta which increases maternal insulin resistance to produce hyperglycemia in order to provide enough glucose for the developing fetus; implicated in the etiology of gestational diabetes mellitus (3 words).
  4. 6. Part of "HELLP;" aggregation of platelets and reduced thrombopoietin production from the liver result in this (3 words).
  5. 7. Condition in which a previously normotensive person experiences a rise in blood pressure >140/90 after 20 weeks; increases risk of pre-eclampsia (acronym).
  6. 8. Glucose intolerance diagnosed during pregnancy; risk factors include advanced maternal age, obesity, family history or prior pregnancy with this condition (acronym).
  7. 10. The only way to resolve eclampsia is by delivering this.
  8. 17. High blood pressure (>140/90) with proteinuria; may or may not have symptoms (swelling, headache, vision changes, RUQ discomfort).
  9. 19. Calcium channel blocker used to treat GHTN.
  10. 21. Beta blocker used to treat GHTN.
  11. 22. Severe preeclampsia marked by the onset of seizures.
  12. 25. Preeclampsia may result in frontal headaches and visual disturbances including blurred or reduced vision or light sensitivity, due to an increase of this (acronym).