Abdel -Path 2

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Across
  1. 1. Autoimmune disease with ANAs and wire loop lesions
  2. 7. Serologic marker elevated in PSGN
  3. 10. Elevated BUN and creatinine from reduced GFR
  4. 12. Kidney disease caused by chronic hyperglycemia leading to GBM thickening and sclerosis
  5. 14. Proteinuria hypoalbuminemia hyperlipidemia generalized edema
  6. 18. Life saving intervention in severe ATN or renal failure
  7. 19. Site of back pain in pyelonephritis
  8. 21. Plasma cell malignancy associated with AL amyloid
  9. 23. Light chain amyloid associated with primary amyloidosis and multiple myeloma
  10. 25. End stage kidney disease with scarred hypocellular glomeruli
  11. 27. Deposition of misfolded protein fibrils eosinophilic and extracellular
  12. 29. Cylindrical RBC accumulations in urine diagnostic for nephritic syndromes
  13. 30. Histologic stain for amyloid shows apple green birefringence
  14. 31. Decreased urine output seen in ATN and nephritic syndromes
  15. 32. Congestion seen grossly in infected or inflamed kidney
  16. 33. Retrograde urine flow predisposes to pyelonephritis
  17. 34. Patchy tubular necrosis due to shock and hypoperfusion
  18. 35. Capillary BM thickening due to immune complex deposition in lupus nephritis
Down
  1. 2. Enlarged tongue often due to amyloidosis
  2. 3. Hematuria oliguria azotemia hypertension RBC casts
  3. 4. Thin barrier that thickens in diabetic nephropathy and lupus
  4. 5. Most common cause of acute renal failure reversible
  5. 6. Histology of PSGN with mesangial endothelial proliferation
  6. 8. Malar rash in SLE worsens with sun exposure
  7. 9. Blood in urine hallmark of nephritic syndromes
  8. 11. Nodular glomerulosclerosis, hallmark lesion in diabetic nephropathy
  9. 13. Bacterial infection of renal pelvis usually ascending from UTI
  10. 15. Dominant inflammatory cells in acute pyelonephritis
  11. 16. Immune complex GN after strep throat or skin infection
  12. 17. Most common pathogen in acute pyelonephritis
  13. 20. Amyloid from serum amyloid A linked to chronic inflammation
  14. 22. Expansion of mesangial matrix in glomeruli; diffuse or nodular
  15. 24. Diffuse PCT necrosis due to toxins aminoglycosides metals solvents
  16. 26. Pus in urine leukocyte casts in pyelonephritis
  17. 28. Streptococcal antigen that triggers immune complex GN