Ace Inhibitor/Lisinopril PI

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Across
  1. 4. Dry,persistent;classic Ace inhibitors side effect.
  2. 7. Can occur with volume depletion or high diuretic dose.
  3. 8. Low sodium increases risk of hypotension; start low and go slow.
  4. 12. Peptide increased by ACE blockade, contributes to cough and angioedema.
  5. 14. Dysgeusia reported with Ace Inhibitors.
  6. 15. Common adult starting dose.
  7. 17. Typical dosing of Lisinopril frequency.
Down
  1. 1. Bilateral disease increases risk of acute kidney injury with Ace Inhibitors
  2. 2. Hormone decreased promoting natriuresis and lowering potassium secretion.
  3. 3. Drug class that blocks conversion of Angiotensin I to Angiotensin II.
  4. 5. Site where pressure falls with Ace inhibitors protecting kidneys.
  5. 6. Contraindicated due to fetal toxity
  6. 9. Supplements or salt substitutes can increase risk of Hyperkalemia.
  7. 10. Indicated to reduce morbidity/mortality;improves symptoms via afterload reduction.
  8. 11. Substrate converted to Angiotensin II;accumulates when Ace is inhibited.
  9. 13. Enzyme released by juxtaglomerular; initiates RAS upstream of Ace.
  10. 16. Class risk from reduced Aldosterone;caution with potassium supplements.