Activity No. 3: Transdermal Drug Delivery System

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Across
  1. 1. – Drug property favoring partitioning into lipid bilayers of stratum corneum.
  2. 4. Release – Continuous and predictable release of drug through skin.
  3. 6. – Devices that create painless microchannels in stratum corneum.
  4. 7. – Antihypertensive studied for transdermal delivery.
  5. 10. – Ultrasound-assisted penetration enhancer.
  6. 11. – Essential property for proper contact between patch and skin.
  7. 13. – Chemical added to temporarily increase skin permeability.
  8. 14. – Entry of drug through skin layers.
Down
  1. 2. – Electrical method that facilitates transport of ionized drugs.
  2. 3. – Patient education on proper application and site rotation.
  3. 5. – Transdermal patch drug used for smoking cessation.
  4. 6. – Patch where drug is dispersed within a polymer for diffusion-based release.
  5. 8. – TDDS design where drug is held in a compartment, released via membrane.
  6. 9. – Common dosage form in TDDS.
  7. 12. Corneum – Outermost skin barrier composed of keratinized cells.