Adaptive & Innate Immunity

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Across
  1. 5. Multiprotein complex in innate cells that activates inflammatory cytokines such as IL-1β.
  2. 8. A large phagocytic cell derived from monocytes that engulfs pathogens and presents antigens.
  3. 10. The most abundant white blood cell; first responder to infection, specialized in pathogen destruction.
  4. 11. Molecules that present antigen fragments to T cells.
  5. 14. A group of plasma proteins that enhances phagocytosis and cell lysis.
  6. 15. The ability of the immune system to respond more rapidly and effectively upon re-exposure to an antigen.
  7. 16. CD4⁺ T cell that coordinates immune responses through cytokine secretion.
  8. 18. Cytokines that inhibit viral replication and activate immune cells.
  9. 19. Cell responsible for humoral immunity; differentiates into plasma and memory cells.
Down
  1. 1. Lymphocyte of the innate immune system that kills infected or tumor cells without prior sensitization.
  2. 2. Any substance capable of inducing an immune response by binding to specific receptors on lymphocytes.
  3. 3. cell Antigen-presenting cell that links innate and adaptive immunity by activating T cells.
  4. 4. Immune protection mediated by antibodies in body fluids.
  5. 6. Immunoglobulin molecule secreted by plasma cells that binds specifically to antigens.
  6. 7. CD8⁺ T cell that directly kills infected or abnormal cells.
  7. 9. The process by which immune cells engulf and digest pathogens or debris.
  8. 12. Small signalling proteins released by immune cells to regulate immunity, inflammation, and hematopoiesis.
  9. 13. Process by which lymphocytes with receptors specific for an antigen are activated and proliferate.
  10. 17. The specific part of an antigen recognized by an antibody or T cell receptor.