ADH and Urea Baby!
Across
- 2. is a hormone that increases water permeability in collecting ducts.
- 3. ADH stimulates reabsorption of urea in this part of the nephron to maximize corticopapillary osmotic gradient.
- 6. excess nitrogen is converted to this molecule which is then excreted by the kidneys.
- 7. is decrease with release of ADH while urine osmolarity is increase.
- 8. is a common treatment for central diabetes insipidus.
- 9. is characterized by excessive free water retention and euvolemic hyponatremia with continued urinary Na excretion.
- 12. pituitary ADH is synthesize by the hypothalamus and stored and secreted in this area of the brain.
- 13. is a drug that is known to cause nephrogenic diabetes insipidus where V2 receptors are damage and don't respond to ADH analogue
Down
- 1. is the amino acid that is converted to urea and ornithine in the urea cycle.
- 2. are the channels upregulated by ADH binding to V2 and increasing H20 permeability at the collecting duct.
- 4. is the pathway used by ADH when binding V2 receptors to increase water reabsorption.
- 5. is a condition characterized by inability to concentrate urine.
- 10. is the pathway used by ADH when binding V1 receptors and inducing vascular smooth muscle contraction.
- 11. urea is metabolized by this organ and then excreted by the urine.