ALM3

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Across
  1. 3. The stem cell niche often includes a _______ zone, where stem cells are maintained in a quiescent state and can be activated as needed
  2. 4. One key characteristic of adult stem cells is their ability to _______ into various cell types specific to their tissue of origin
  3. 5. In bone marrow, stem cells called _______ cells can give rise to different types of blood cells, including red blood cells, white blood cells, and platelets
  4. 9. Niche in the brain contains neural stem cells and is characterized by a supportive network of astrocytes and blood vessels
  5. 11. The process by which adult stem cells divide and produce more stem cells, as well as differentiated cells, is known as
  6. 13. Cells within the niche that produce signaling molecules to regulate stem cell behavior, such as growth factors and cytokines
  7. 14. In the intestinal epithelium, the _______ niche is located at the base of the crypts and is critical for maintaining intestinal stem cells and promoting cell turnover
  8. 15. The zone in the bone marrow niche that is involved in regulating the interaction between hematopoietic stem cells and the surrounding cells
Down
  1. 1. Niche that supports hair follicle stem cells and is involved in regulating hair growth cycles
  2. 2. Unlike embryonic stem cells, adult stem cells are _______ and do not pose the same ethical concerns related to their source
  3. 6. matrix The component of the niche that provide a scaffold for stem cells.
  4. 7. Signaling pathway that is crucial in many niches for regulating stem cell proliferation and differentiation
  5. 8. A specialized microenvironment within a tissue that maintains the stem cells in their undifferentiated state and regulates their function
  6. 10. Stem cells are a type of adult stem cell that can develop into any type of cell in the body, but are usually limited to the tissue
  7. 12. cells in the niche secrete factors that regulate stem cell activity and help maintain the balance between stem cell self-renewal and differentiation