Anticonvulsants

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Across
  1. 2. A major challenge with anticonvulsant therapy: poor _____ _____
  2. 5. Excretion type for Keppra
  3. 9. CYP enzyme ______ with phenobarbital causing drugs to be cleared faster & may need to increase dose
  4. 10. A common form of administering diazepam
  5. 11. A dose-dependent effect of phenobarbital in dogs
  6. 12. Used to treat status epilepticus in cats & dogs
Down
  1. 1. The only anticonvulsant approved in Canada
  2. 3. An anticonvulsant that does renal elimination and an extremely long half life (not for cats though)
  3. 4. Excretion type for diazepam
  4. 6. Aka Keppra - give during status epilepticus
  5. 7. __-______ kinetics may occur in cats on phenobarbital - minor changes in dose result in large fluctuations in blood levels
  6. 8. A food interaction to consider with KBr