Antivirals

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Across
  1. 4. A combination treatment that includes both Ledipasvir and sofobuvir.
  2. 6. A herpesvirus pro-drug.
  3. 8. Because viruses reproduce so quickly and make frequent changes during replication, antivirals must be very potent and attack the virus in multiple ways to prevent ______.
  4. 9. The brand name influenza antiviral that inhibits NA.
  5. 11. We now have drugs to cure _____ _ virus.
  6. 13. Drug that blocks neuraminidase activity and helps prevent influenza virus transmission.
  7. 14. Xofluza, also known as _____, blocks cap snatching.
  8. 17. Inhibits SARS coronavirus protease.
  9. 18. Saquinavir inhibits HIV _____.
Down
  1. 1. Until we have better ______ finding antivirals for acute infections will not be very useful.
  2. 2. Antiviral with activity against several RNA viruses.
  3. 3. Many antivirals are _____ analogs. They get incorporated into viral genomes and either induce mutation of chain termination.
  4. 5. Reverse transcriptase inhibitor that prevents polymerization.
  5. 7. Fuzeon is an antiviral that blocks viral entry by binding to the envelope and prevents 6HB formation and viral ____.
  6. 10. An antiviral that targets the host cell and prevents virus binding.
  7. 12. Most of the antivirals used currently treat ____ infections.
  8. 15. The first drug identified to treat HIV.
  9. 16. To prevent infection with HIV, people in high-risk groups can take ____.