Autoimmunity and the Thyroid

123456789101112131415
Across
  1. 2. Female hormone that plays a role in auto-antibody production
  2. 5. receptor antibodies found in Grave's
  3. 7. Hypersensitivity mediated by immune-complex and complement proteins, mainly resulting in systemic deposition usually implicated in SLE
  4. 9. Hypersensitivity involving IgE, mast cells, basophils and eosinophils
  5. 10. enzymes that oxidises iodide ions and targeted by auto-antibodies in the thyroid
  6. 12. produced in the follicular cells targeted by auto-antibodies in the thyroid
  7. 13. Deletes immature T or B cells that posses self antigen receptors
  8. 14. Treatment for slowing proliferation of lymphocytes
  9. 15. T cells have a strong association with inducing autoimmune responses
Down
  1. 1. Renders mature, self reactive lymphocytes inactive
  2. 3. Inactivation of a T-Cell when encountering an antigen without appropriate costimulation
  3. 4. T cells that protect against the development of autoimmunity.
  4. 6. Disease that occurs as a result of Th and Tc cells being activated against self antigens
  5. 7. Hypersensitivity mediated by cytotoxic T cells, IgG and IgM and responsible for Graves's Disease and Type 1 diabetes
  6. 8. Antigens that induce tolerance
  7. 11. T cells mainly involved in development of autoimmunity