BHS 316 Exam 2

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Across
  1. 3. These kind of molecules can be expressed by any time of cell (two words).
  2. 5. These vaccines have been made against weakened forms of the pathogen that are unable to cause disease in healthy individual but retain antigens that generate memory.
  3. 7. These vaccines have been made from isolating non-dangerous proteins from a pathogen that can elicit an immune response but not cause infection.
  4. 8. These plasma B cells are produced in germinal centers and later reside in bone marrow, producing small amount of antibodies over a long period of time (two words).
  5. 10. These are the secreted proteins produced by dendritic cells (DCs) after leaving the battle site (the area of infection).
  6. 12. These vaccines have been made from parts of toxins that have been modified or weakened but otherwise “appear” normal.
  7. 16. The process by which an infected cell’s DNA is destroyed by the cells own enzymes.
  8. 19. T cells whose job is to downregulate the immune system.
  9. 22. This type of T cell inspects the peptides presented on class I MHC molecules.
  10. 23. Both CTLs and NK cells can kill infected cells using perforin/granzyme and ____.
  11. 25. IL-6 and TGFb are cytokines that cause uncommitted T helper cells to become this class of T helper cell(two letters followed by two numbers).
  12. 26. The idea that an exogenous antigen could be displayed by a class I MHC molecule (two words).
  13. 28. These T cells expresses only CD4 or CD8 rather than both (two words).
  14. 30. These vaccines have been made from whole organisms that have been “killed” chemically but otherwise “appear” normal (two words).
  15. 31. In order to prevent an autoimmune disease, this process is about keeping T cells that recognize foreign peptides as opposed to self peptides (two words).
  16. 32. These vaccines have been made against viruses using genetic engineering to isolate specific viral proteins.
Down
  1. 1. T cells are born in the bone marrow and are taught self tolerance initially when they leave the bone marrow and move to this location.
  2. 2. This is the place where B cells are educated to tolerate self (two words).
  3. 4. The protein molecules that display lipids instead of the classical peptides (two letters followed by a number).
  4. 6. These vaccines have been made from organisms that cannot cause disease but otherwise “appear” normal.
  5. 9. These types of NK, T, and B cells all go through some level of “tolerance” training.
  6. 11. The portion of the invariant chain that occupies the class II MHC groove in an endosome.
  7. 13. If an NK cell comes upon another cell in your body that produced no class I MHC molecules, it will kill that cell because it is missing this principle (two words).
  8. 14. The concept that immune cells can recall pathogens they have seen in the past.
  9. 15. This type of protein is presented by class II MHC molecules and are presented to helper T cells.
  10. 16. These molecules are activated T cells have license to visit specific areas of the body, and their ability to visit a site. They are also the “passport” that Virgin T cells have that allow them to visit specific sites in the body.
  11. 17. lived These plasma B cells are produced in lymphoid follicles and the early stages of invasion and travel to the bone marrow to produce massive quantities of antibodies (two words).
  12. 18. These memory T cells stay in the secondary lymphoid organs and wait to produce activated T cells in the future.
  13. 20. The group of chemical messengers secreted by helper T cells that serve to provide instructions to the rest of the immune system.
  14. 21. The main purpose of this is to organize and concentrate antigen presentation to increase the chance of lymphocytes finding their cognate antigen (two words).
  15. 24. These vaccines use genetic engineering to trick a virus that can’t hurt us into putting a single gene from a pathogenic microbe in our cells. That gene will then make the one protein from the pathogenic microbe inside our cells, but since it’s only one protein it can’t hurt people.
  16. 27. IL-4 is a cytokine that causes uncommitted T helper cells to become this class of T helper cell (two letters followed by one number).
  17. 29. This type of protein is presented by class I MHC molecules and are presented to killer T cells.