BHS316 Exam 2

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Across
  1. 2. This complex of membrane proteins works with alpha and beta proteins to transmit the signal to T cell nucleus
  2. 3. Protein that releases CLIP, allowing exogenous peptides to bind to class II groove
  3. 5. Orientation of the ends of the binding groove for Class I MHC molecules
  4. 7. T cells that don't have CD4 or CD8 receptors on their surface
  5. 10. Protein molecules that present lipids to T cells
  6. 11. This cytokine decreases T cell proliferation and makes CTLs less vicious
  7. 14. The complement pathway that IgM is associated with
  8. 16. Cuts proteins into small peptides to be loaded onto MHC molecules
  9. 18. Release from macrophages or neutrophils, helps to activate DCs
  10. 19. Stage of dendritic cell activity, not good APCs and express B7 in moderate amounts
Down
  1. 1. Antibody that coats pathogens and is secreted in breast milk
  2. 2. This receptor is expressed by CTLs that clips on to Class I MHC
  3. 4. Act to refuel activated T cells that leave the node
  4. 5. T cells express these receptors that bind to B7 protein and deactivate the immune system
  5. 6. B cells bind to this, a process in which the immune system has gone wrong
  6. 8. This cytokine is produced by Th17 helper T cells and increases the number of neutrophils
  7. 9. The binding of this ligand on T cells to its receptor on B cells is the co-stimulatory signal for B cell activation
  8. 12. This cytokine is produced by DCs to stimulate T cells to become Th1 helper T cells
  9. 13. Combinations of these cause B cells to switch classes
  10. 15. This type of T cell dampens the immune response, prevents over-reactivity
  11. 17. This lymphoid organ is an "open house" to blood