BI2010 Beyond the Cell Crossword Puzzle!

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Across
  1. 3. This refers to the surface of the cell that faces the lumen
  2. 6. This adhesive molecule found in plants is a glycoprotein involved in the complex network that cellulose microfibrils are enmeshed in.
  3. 7. These plant-specific junctions share a similar functionality to gap junctions in animal cells.
  4. 8. This refers to the surface of the cell that faces/is connected to the basement membrane
  5. 10. These cell-cell junctions prevent the movement of molecules across cell layers
  6. 11. These membrane-spanning proteins protrude into the gap between cells and join plasma membranes together in gap junctions.
  7. 13. These amino acid sequences are required for fibronectins to be recognized by integrins for proper binding.
  8. 16. This process refers to when tight junctions block the passage of other molecules in the extracellular fluid
  9. 17. This linear carbohydrate molecule is what makes up the structural fibers of plant cells
  10. 19. These cell-ECM attachments function in cell-ECM adhesion, feature localized points of attachment, and are associated with actin microfilaments
  11. 22. This component of the plant cell hydrated matrix that cellulose microfibrils are enmeshed in is a branched polysaccharide that acts as a glue which holds cells together (it is NOT classified as an adhesive molecule).
  12. 25. This protein structural fiber provides the elasticity and flexibility required by some tissues, is crosslinked by covalent bonds between lysine residues, and is very rich in glycine and proline.
  13. 27. This enzyme is responsible for converting procollagen to collagen once it has been secreted from the cell.
  14. 28. These are a family of transmembrane proteins that act as receptors on the plasma membrane. They recognize and bind to fibronectins and laminins on the outside of cells and are the primary means by which cells bind to ECM proteins. They also make 2 main types of connections to the cytoskeleton on the inside of cells, and they regulate cell movement, attachment, and signaling.
  15. 29. These glycoproteins have many glycosaminoglycans attached to a single protein molecule and create a hydrated, gel-like network in which collagen and elastin fibrils are enmeshed.
  16. 30. These allow cells to attach to each other and to extracellular structures (general)
Down
  1. 1. This is the extracellular structure that surrounds most plant cells, providing them with rigidity and serving as a permeability barrier.
  2. 2. 6 of these protein units come together to form the flower-like protein structure that join cells together in gap junctions
  3. 4. These transmembrane proteins are associated with tight junctions
  4. 5. This process refers to when tight junctions allow the passage of some molecules from the extracellular fluid
  5. 9. These adhesive junctions feature continuous zones of attachment and are associated with actin microfilaments, acting like “stitches” for connecting cells together.
  6. 12. These cell-cell junctions link adjoining cells to each other
  7. 14. This structure serves as a structural support that maintains tissue organization and acts as a permeability barrier that regulates the movement of molecules and cells. It consists of type IV collagen, proteoglycans, laminins, and entactin (or nidogen), and underlies epithelial cells, separating them from connective tissues
  8. 15. These adhesive junctions feature localized points of attachment and are associated with intermediate filaments (tonofilaments), acting like “nails” for connecting cells together.
  9. 18. This component of the plant cell hydrated matrix that cellulose microfibrils are enmeshed in is a branched polysaccharide that acts as a structural filler, binding to cellulose to provide rigidity and support to the cell wall
  10. 20. These cell-ECM attachments function in cell-basal lamina adhesion, feature localized points of attachment, and are associated with intermediate filaments (tonofilaments)
  11. 21. These adhesive glycoproteins can occur in soluble form in body fluids, as insoluble fibrils in the ECM, and as an intermediate form loosely associated with cell surfaces. They have different forms due to alternative splicing, and they consist of two large polypeptide subunits linked near their carboxyl ends by disulfide bonds
  12. 23. This protein structural fiber is the most abundant component of the ECM in animals, forms fibers with high tensile strength, and occurs as a triple helix with an unusual amino acid composition.
  13. 24. These cell-cell junctions allow direct electrical and chemical communication between cells
  14. 26. These adhesive glycoproteins are found mainly in basal lamina and act as a bridging molecule that attaches cells to basal lamina. They’re composed of 3 long polypeptide chains held together by disulfide bonds and have domains that include binding sites for collagen, heparin, heparan sulfate, entactin, etc.