BIOL204-Lymphatic system & Immunity

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Across
  1. 3. movement of cells toward a chemical signal
  2. 5. antibody-mediated clumping of pathogens
  3. 9. microbial molecules recognized by innate immune receptors (abbreviation, singular)
  4. 11. T cell-rich zone in lymph nodes
  5. 13. complement pathway triggered by lectins such as MBL
  6. 15. antibody region that determines class and function
  7. 18. first word in MBL that triggers complement activation
  8. 19. prostaglandin that raises hypothalamic temperature setpoint
  9. 20. ability of lymphocytes to recognize a specific antigen
  10. 23. cell derived from B cell that secretes antibodies
  11. 24. substance that induces fever, like IL-1 or IL-6
  12. 25. type of basement membrane in lymphatic capillaries
  13. 31. substance that activates adaptive immune defenses
  14. 34. molecules that present peptide antigens to T cells (abbreviation)
  15. 35. antibody region that binds specific antigens
  16. 37. T cell that activates other immune cells (CD4+)
  17. 38. segment between valves in collecting lymphatic vessels
  18. 40. lymphoid follicles with germinal centers
  19. 41. chemical from mast cells that increases vasodilation and permeability
  20. 42. professional antigen-presenting cells
  21. 43. protein complex that forms pores in microbe membranes (abbreviation)
Down
  1. 1. cells that transport antigens from intestinal lumen to Peyer’s patches
  2. 2. lymphoid follicles with naïve B cells
  3. 3. T cell that kills infected or abnormal cells (CD8+)
  4. 4. type of thymic selection eliminating self-reactive T cells
  5. 6. node structures that receive lymph from collecting lymphatic vessels
  6. 7. antibody function that blocks pathogen binding to host
  7. 8. junction; connect lymphatic endothelial cells in lymphatic capillaries
  8. 10. long-lived lymphocyte that responds quickly upon re-exposure
  9. 12. molecules like antibodies or C3b that tag pathogens for phagocytosis
  10. 14. induces artificially acquired active humoral immunity
  11. 16. type of thymic selection ensuring T cells recognize MHC
  12. 17. first word in the abbreviation for PRRs
  13. 19. accumulation of fluid in tissues causing swelling
  14. 21. coating of pathogens to enhance phagocytosis
  15. 22. part of an antigen recognized by immune receptors (also known as antigenic determinant)
  16. 26. group of identical B or T cells with same antigen specificity
  17. 27. lymphatic duct that drains lymph from most of the body
  18. 28. veins where lymph enters venous circulation
  19. 29. protein system that enhances innate immune responses
  20. 30. complement pathway triggered by spontaneous activation of C3b
  21. 32. antiviral cytokines released by infected cells
  22. 33. migration of leukocytes through vessel walls into tissues
  23. 36. Immunoglobulin E is involved in this and parasite defense
  24. 37. type of immunity involving plasma cells and antibodies
  25. 39. complement pathway activated by antigen–antibody complexes