Biology of a Cancer Cell

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Across
  1. 2. the cancer that is the leading killer in both men and women in recent years.
  2. 3. Tissue Inhibitors of Metalloproteases.
  3. 6. Histone deacetyl transferases
  4. 7. rapid response immunity; most animal species do not possess this immunity
  5. 8. named after a crab, when tumor cells become malignant
  6. 9. binds to and activates caspase 9 (initiating caspase) for the Intrinsic Pathway
  7. 11. sister chromatids segregate towards opposite poles
  8. 13. critical in activating the WNT pathway in colon cancer, 80% of all colon cancers have mutations in this gene
  9. 14. group of proteases capable of eating a cell within
  10. 16. cancers of the blood
  11. 18. genes that, when hyperactive, promote cancer development
  12. 22. the formation of new blood vessels
  13. 23. immunity that is ‘educated’ from a previous encounter
  14. 24. “disassembly” of the cell
Down
  1. 1. when a tumor mass is contained, and cells are not able to wander.
  2. 4. process where cancer cells leave the tumor and enter the bloodstream through small vessels
  3. 5. uncontrolled cells growing in a solid mass
  4. 6. abnormal increase in amount of normal looking cells in a tissue
  5. 10. Hereditary Non-Polyposis Colorectal Cancer
  6. 12. programmed cell death
  7. 15. the study of the distribution and prevalence of disease, but does NOT establish cause
  8. 17. Inhibition the signal that stops cells from dividing when in contact with their neighboring cells
  9. 19. Matrix metalloproteinases
  10. 20. RNA containing multi-subunit, that adds DNA sequences to the chromosome’s 3’ end.
  11. 21. complete loss of differentiation