NAPLEX - Boxed Warnings #1

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Across
  1. 3. Commonly used antihypertensive associated with fetal toxicity
  2. 4. Brand name immunosuppressive agent that increases the risk of malignancies
  3. 6. Increased risk of cardiovascular events with this xanthine oxidase inhibitor
  4. 8. HIV medication associated with hypersensitivity reactions
  5. 10. Risk of HIV drug resistance when used in PrEP therapy in undiagnosed HIV infection
  6. 12. Oncology agent that carries a dose-dependent risk of nephrotoxicity
  7. 13. Carries a boxed warning with regard to switching between different dosage forms/brands
  8. 15. Reduced bone mineral density
  9. 19. Pulmonary hypertension medication that may cause hepatotoxicity
  10. 20. Type of cancer associated with the use of unopposed estrogens in postmenopausal women
  11. 22. Medication used to treat anemia that carries a warning for cardiovascular risks when hemoglobin levels rise above 11
  12. 23. Avoid the use of this PAD medication in patients with CHF
  13. 24. Increased heart failure risk with this diabetes class
  14. 25. Potassium-sparing diuretic that can cause severe hyperkalemia
Down
  1. 1. Agranulocytosis
  2. 2. Lethal skin reactions
  3. 5. Potential option in treating NMS which has a boxed warning for hepatotoxicity
  4. 6. Tendon rupture
  5. 7. Increased risk of asthma-related death when monotherapy is used
  6. 8. Increased mortality in older patients with dementia-related psychosis
  7. 9. This cardiology agent can cause pulmonary toxicity
  8. 11. Carries a boxed warning for ineffectiveness when used in patients who are poor metabolizers at the CYP2C19 enzyme
  9. 14. Brand name of an ADHD medication associated with an increased risk of suicidal ideation in pediatric patients
  10. 16. Seizure medication that causes hepatotoxicity
  11. 17. Desmopressin carries a boxed warning for this adverse effect
  12. 18. Suicidal ideation in younger patients
  13. 21. Respiratory depression