Cancer

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Across
  1. 6. The spreading of a tumor to different parts of the body.
  2. 11. ___________ microbiome are one of the hallmarks of cancer cells. Variability in the microbiomes between individuals in a population can have a
  3. 13. the mutated, overactive version of a proto-oncogene that can lead to uncontrolled cell growth and cancer.
  4. 14. Cancer cells tend to have highly abnormal chromosomes, reflecting their genetic ___________.
  5. 15. This describes the process of cancer cells entering blood vessels
  6. 17. normal genes that regulate cell growth and division.
  7. 19. The aberrant physical properties of the tumor microenvironment can induce broad ____________changes, leading to clonal outgrowth of cancer cells with enhanced fitness for proliferative expansion.
  8. 20. Phentoypic __________ allows cells to escape or evade terminal differentiation, which is a critical component of cancer pathogenesis.
Down
  1. 1. Enzymes that cancer cells use to break down the extracellular matrix.
  2. 2. This describes the process of cancer cells leaving blood vessels
  3. 3. A tumor is expected to have _____________ apoptosis(increased or decreased)
  4. 4. Cancer cells attach to this to invade
  5. 5. These cells secrete signal molecules that act in a
  6. 7. impact on cancer phenotypes
  7. 8. Describes a tumor that can metastasize
  8. 9. What is considered the leading risk factor for cancer?
  9. 10. This is a modifiable risk for cancer.
  10. 12. fashion and contribute to tumor phenotypes.
  11. 16. Controlled cell death.
  12. 18. a group of diseases characterized by the uncontrolled growth and division of cells that can invade surrounding tissues or spread to other parts of the body.