Cardio: Blood cell formation 1

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Across
  1. 4. Lifecycle: Bone marrow formation 2-6 days. Time in blood < 1 hr. Time in tissue 2 weeks
  2. 5. Lifecycle: Bone marrow formation 2.5 days. Time in blood 1 day. Time in tissue weeks-years
  3. 6. decreased in size more, nucleus is smaller and dark purple, and cytoplasm is now polychromatic in color
  4. 10. decreased size, nucleus is smaller and cytoplasm is still deep blue
  5. 11. what does the rubriblast need stimulation from to differentiate into an erythrocyte?
  6. 15. Lifecycle: Bone marrow formation 7-8 days. Time in blood ~110 days (depending on species)
  7. 16. Lifecycle: Bone marrow formation 3 days. Time in blood 8-10 days.
  8. 18. what do lymphoblasts develop into?
  9. 19. Which stem cells differentiate into myeloblasts, monoblasts, rubriblasts, and megakaryoblasts
  10. 21. if the rate of destruction of erythrocytes exceeds the rate of production for very long the result will be:
  11. 22. Lifecycle: Bone marrow formation 2.5 days. Time in blood 6 hrs. Time in tissue 2 weeks
  12. 23. what do megakaryoblasts develop into?
  13. 25. which blast cells develop into neutrophils, eosinophils, and basophils?
  14. 26. slightly larger than a mature RBC, no nucleus is present, cytoplasm is still polychromatic (Horses don't release these)
Down
  1. 1. Lifecycle: stored in lymph nodes. Bone marrow/thymus formation 6-8 hrs. Time in blood variable. Time in tissue up to 10 yrs.
  2. 2. almost as small as a mature RBC, nucleus is small and black (pyknotic), and cytoplasm is polychromatic
  3. 3. what do monoblasts develop into?
  4. 7. large in size with a large, round, lacy, red purple nucleus and deep blue cytoplasm
  5. 8. where is EPO produced?
  6. 9. approximately what percentage of circulating RBC's are replaced daily?
  7. 12. 6-9 µm in size, no nucleus, and cytoplasm is now pink.
  8. 13. what do rubriblasts develop into?
  9. 14. the continual formation of all blood cells
  10. 17. in inactive marrow, the space formerly occupied by hematopoietic cells is filled with ____
  11. 18. what blast cells do lymphoid stem cells differentiate into?
  12. 20. erythropoietin production is stimulated by:
  13. 23. what can high concentrations of EPO cause?
  14. 24. Lifecycle: Bone marrow formation 3-5 days. Time in blood 7-14 hrs. Time in tissue 3 days.