catst

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Across
  1. 1. A specialized genomic library of defenses drafted when phosphorylated messengers fly from the JAK signal to the promoter to build internal walls against a virus.
  2. 5. A measure of the lead actor's maximal performance, which reaches its tragic peak when a cholera toxin jams the alpha subunit's GTPase activity.
  3. 6. The specific genomic landing strip where a dimerized steroid-receptor complex binds to rewrite the cell's script [Wordlist].
  4. 7. The elite escort that carries the four-ringed raw material into the mitochondrial furnace to begin the production of life's steroid messengers.
  5. 9. A single typo in the stable library during the fast read that leaves the JAK partner without its natural USP18 off-switch.
  6. 11. A vasodilating pain messenger born when biological editors snip the calcitonin script to scream "migraine" to the brain.
  7. 13. The tissue's lead "paracrine gossip" that uses local channels to tell mitochondria-rich makers to start the stomach’s acid rain.
  8. 16. A calming, non-packaged traveler that skips the vesicle stage to slip through membranes and modulate the tail of a swimmer.
  9. 17. The scheduled demolition and regression of the monthly yellow factory when the messenger of pregnancy fails to arrive.
  10. 18. The gastric laborer that secretes an inactive version of the lead actor, waiting for acid to cut the ribbon on its performance.
  11. 19. A sensory lie where the "Gate" fails, causing the brain to interpret a gentle, non-noxious greeting as a painful assault.
  12. 20. A permanent chemical tag added by a comma-shaped visitor to jam a molecular traffic light in the green position, turning Sutherland's second messenger into an intestinal flood.
Down
  1. 2. The muscle's economical terminator that sweeps the primary cation back into its sarcoplasmic warehouse to end the squeeze.
  2. 3. The measure of a host's loyalty to the doctor's script, ensuring the drug guest arrives at the target at the right dose and time.
  3. 4. The thick-filament workhorse that refuses to perform its sliding act until a kinase provides a phosphate power-up in response to a Calcium signal.
  4. 8. The molecular "off-switch" on a trimeric traffic light; when broken, it allows Adenylyl Cyclase to keep turning ATP into a secondary messenger flood
  5. 10. The critical journey of a phosphorylated messenger moving the viral war plans from the receptor's shadow into the genomic library.
  6. 12. The "shoulders to cry on" nervous system that uses short pre-messengers to tell your resistance arteries to tighten the pressure.
  7. 14. A sideways slide on a dose-response curve defining how little of a blocker is needed to silence a spliced pain message like CGRP.
  8. 15. The metabolic toll taken by the hepatic gateway during a drug's journey, leaving only a fraction of the survivors to reach the systemic circulation.