Causes of agitation

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Across
  1. 3. A paradoxical problem, but can be a solution
  2. 6. To the well organised mind, < > is but the next great adventure (Dumbledore, 1997)
  3. 8. What's the A in PVA?
  4. 12. To be truly holistic is to consider this
  5. 13. Performance enhancing 'no-no'
  6. 14. With these, they say you're in the class A team.
  7. 15. Contagion
  8. 16. It's all in your head
Down
  1. 1. Failing to follow the motto: 'Prunes, legumes, H20 and 'go''
  2. 2. llmmnnpp
  3. 4. Cicely went to a boulangerie and bought some ?
  4. 5. 40 a day won't keep this doctor away
  5. 7. A shocking refreshment in your sports drink
  6. 9. To hold it in, you can't let it out
  7. 10. Dry
  8. 11. Mezolar matrix