Cell Biology Crossword 2

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Across
  1. 5. Type of lymphocyte that is predominately made in the thymus. It plays a central role in cell-mediated immunity.
  2. 8. The term that describes the growth of microfilaments. Subunits are added onto one end of the filament while subunits are removed from the other end
  3. 9. Drug that can be used to stop cell crawling by inhibiting RNA polymerase and stabilizing filaments.
  4. 13. Form of immunity mediated by circulating antibodies, which coat the antigens and target them for destruction
  5. 15. The protein subunit of microtubules
  6. 18. Anchoring cell-cell junction, usually formed between two epithelial cells.
  7. 20. Moves cargo on microtubules in the plus direction. Their linker domain is responsible for the size step they take.
  8. 21. Motor proteins that move along actin filaments
  9. 23. Addition of one or more sugars to a protein or lipid molecule
  10. 24. Type of vaccine made from a toxin that has been chemically modified.
  11. 27. The primary function of these proteins is to facilitate membrane fusion.
  12. 28. Complex of proteins that nucleates actin filament growth from the minus end
  13. 29. Protein that plays a major role in the formation of coated vesicles.
  14. 30. A drug that can be used as an anti-cancer drug. It binds to and stabilizes microtubules, causing a net increase in tubulin polymerization.
  15. 32. This kind of transport delivers proteins from ER to the Golgi in COPII vesicles
  16. 33. A ER unfolded protein response that involves a cytoplasmic splicing process.
  17. 34. Protein that binds to a GTPase and activates it by stimulating it to release its tightly bound GDP, allowing it to bind GTP in its place.
  18. 35. This kind of junction seals gaps between cells to create epithelial sheets
  19. 36. Type of vaccine created by reducing the virulence of a pathogen.
  20. 37. Type of leukocyte that appears in inflammatory responses.
Down
  1. 1. Enzymes that can bind and hydrolyze guanosine triphosphate (GTP)
  2. 2. Drug that can be used as an anti-cancer drug. It binds to and stabilizes free tubulin which prevents polymerization.
  3. 3. Intermediate filament-type proteins that are the major building blocks of the nuclear lamina.
  4. 4. Type of cell that processes antigen material and presents it on the cell surface to the T cells
  5. 6. A local response of a tissue that is general and non-specific to tissue damage. It is characterized by tissue redness, swelling, heat, and pain.
  6. 7. Cell-cell junction that seals adjacent epithelial cells together, preventing the passage of most dissolved molecules form one side of the epithelial sheet to the other.
  7. 10. Type of lymphocyte that makes antibodies.
  8. 11. Bundle of microtubules and associated proteins that forms the core of a cilium or a flagellum in eukaryotic cells and is responsible for their movements
  9. 12. The kind of cells that the extracellular matrix arises from.
  10. 14. Membrane-bounded organelle in eukaryotic cells containing digestive enzymes. It is normally maintained at a pH below 5.
  11. 16. Target peptide sequence in the amino acid structure of a protein which prevents the protein from being secreted from the ER
  12. 17. Actin-binding protein which allows for the addition to the plus end
  13. 19. Inhibits viral spread from cell to cell and activates natural killer cells to kill virus-infected cells
  14. 22. Type of cell that secretes mucus and protects against microbes
  15. 25. The aggregation disease which results from a build-up of amyloid plaques.
  16. 26. This type of immunity is the third line of defense. It is immunity that occurs after exposure to an antigen either from a pathogen or a vaccination. This part of the immune system is activated when the innate immune response is insufficient to control an infection.
  17. 31. A ER unfolded protein response that involves regulated removal of the sensor protein from the membrane. Its sensor is also a transcription factor.