Cell Biology for Engineers SP 23 Crossword

2. Cause cancer when carrying a loss-of-function mutation
3. This type of cell signaling involves cells proliferating in response to mitogens released by neighboring cells
6. Intercellular channels that facilitate communication among cells in tissue by allowing ions and small molecules to move between adjacent cells
9. The state where cells exit the cell cycle permanently and eventually die
10. Give rise to oncogenes that cause cancer by carrying a gain-of-function mutation
11. Commonly used method to measure tissue stiffness
12. Type of stem cells found in early embryos
15. The gate-keeper for G1-to-S transition
18. The phase in microbial cell growth where cells double exponentially with time with the maximum growth rate
19. Condition of having an abnormal number of chromosomes
20. Cultured stem cells derived from differentiated adult tissues
22. Commonly used scaffold of networks of polymers that swell in water to form a gel-like structure

1. Provides tensile strength to tissues and consists of a triple helix made of the repetitious amino acid sequence glycine-X-Y
4. Mediate adhesion between neighboring cells and between cells and the ECM and help in stress distribution in tissue
5. This pathway plays a key role in regulating the proliferation of intestinal stem cells
7. A process by which cells become more specialized
8. This holds sister chromatids together during metaphase
13. Set the boundary between the apical and basal domains of plasma membrane in epithelial cells
14. This type of cell signaling involves hormones released by endocrine cells traveling through the blood to reach a target cell
16. Composed of a core protein and covalently attached GAGs, providing compressive strength to tissues
17. This type of cell signaling responds to signals from the same cell
21. This type of cell signaling propagates action potential along nerve axons and through synapses