Cell Cycle

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Across
  1. 4. Part of interphase where DNA replication occurs to create sister chromatids
  2. 5. Normal cells become cancerous through ______ in DNA
  3. 7. Type of reproduction that results in genetic diversity in the offspring
  4. 8. Type of reproduction that results in identical clones of the parent
  5. 14. Protein fibers (microtubules) made by the centrioles that pull chromosomes apart during cell division
  6. 15. Phase of mitosis where sister chromatids are pulled away from each other by spindle fibers
  7. 16. Cell that makes up tissues of the body (non-reproductive cells)
  8. 18. The thin, long, stretched out version of DNA (invisible in this form)
  9. 19. Another name for the spindle fibers (the type of cytoskeletal protein fiber they are)
  10. 21. Type of cell division that creates haploid gametes used in sexual reproduction
  11. 23. Phase of mitosis where two new nuclei form around each set of separated chromosomes
  12. 24. Reproductive cells (egg and sperm)
  13. 25. Checkpoint that makes sure DNA has been replicated properly
  14. 29. Chromosome pairs that are the same size, shape and carry info for the same genes
  15. 32. Organisms that contain only one circular chromosome in the cytoplasm
  16. 33. Checkpoint that ensures cell has grown large enough and there is no DNA damage before being replicated
  17. 35. Type of proteins found at cell checkpoints that monitor the cell as it passes from phase to phase
  18. 36. Version of DNA where it coils/condenses into an X shape (becomes visible here)
  19. 37. DNA wraps itself around ____ proteins to become packaged into a more organized structure in the nucleus
  20. 38. Organelle that produces the spindle fibers
  21. 39. Collection of all 8 histone proteins together that help package DNA
Down
  1. 1. Organisms that contain one or more linear chromosomes inside a nucleus
  2. 2. Phase of mitosis where chromosomes become visible, nuclear membrane disintegrates and spindle fibers appear and attach to kinetochore proteins in centromere
  3. 3. Phase of the cell cycle where growth and preparation for cell division occurs
  4. 6. When cancerous cells lose anchorage dependency and separate from the tumor and spread elsewhere in the body
  5. 9. Uncontrolled cell division that results in tumor formation
  6. 10. Checkpoint that ensures all microtubules (spindle fibers) have attached to chromosomes and they have lined up properly
  7. 11. (n) having only one of each chromosome
  8. 12. Programmed cell death that occurs if errors are detected during cell division
  9. 13. (2n) having 2 of each chromosome (one from mom and one from dad)
  10. 17. Protein microfilament that makes up the cleavage furrow in animal cells during cytokinesis
  11. 20. Enzyme that phosphorylates (adds a phosphate group) to target proteins to activate them
  12. 22. Identical copies of chromosomes made prior to cell division during interphase
  13. 26. Proteins located in the centromere where spindle fibers attach to separate chromatids
  14. 27. Phase of mitosis where sister chromatids line up at the equator (middle) of the cell
  15. 28. "Stop/go" signals during the cell cycle that check for errors/mistakes before allowing the cell to move on to the next phase
  16. 30. Phase of cell cycle where cell splits into two independent cells
  17. 31. Holds sister chromatids together prior to division
  18. 34. Type of cell division involved in tissue growth and repair (creates diploid somatic cells)