Cell Metabolism
Across
- 3. any metabolic process that involves the breakdown of complex molecules (such as proteins or lipids) and the release of energy
- 7. abbreviation for an essential metabolite; methyl group donor involved in the methylation of DNA, RNA and histones
- 9. serine/threonine kinase; interacts with Akt, a key player in mammalian metabolism
- 10. Term employed to describe a cellular system used to translocate electrons across impermeable membranes
- 13. By-products of normal oxygen metabolism; can cause irreversible damage to DNA
- 14. State of scarcity of a metabolite, like glucose
- 15. term applied to particular biochemical pathways in which metabolites are newly biosynthesized
Down
- 1. The ______ effect; tumor cell reliance on glycolysis rather than oxidation to meet metabolic needs
- 2. electron donating molecule; used by enzymes to synthesize large biomolecules
- 4. final step of cellular respiration; a series of redox reactions involving the flow of electrons along a series of membrane-bound proteins, coupled with the generation of Adenosine triphosphate (ATP)
- 5. Key part of an important TCA cycle intermediate; consists of a β-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage[3] and 3'-phosphorylated ADP
- 6. endogenous intermediates of metabolism that aberrantly accumulate in cancer cells
- 8. A central cellular respiration pathway, produces NADH and FADH2, occurs in the mitochondria
- 11. deprivation of oxygen, can drive tumor progression
- 12. most abundant free amino acid in circulation; very important in cancer metabolism
- 14. major eukaryotic lipid, named after a legendary mythological creature that creates riddles