Cell Signaling Pathways

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Across
  1. 1. Quickly degraded by a phosphodiesterase into AMP.
  2. 5. Catalyzes the formation of cAMP from ATP.
  3. 6. Protein kinase that is activated by Ras.
  4. 7. Protein kinase that induces cell growth and proliferation.
  5. 8. Converts arginine to NO and citrulline.
  6. 9. Membrane surface receptor with seven transmembrane domains.
  7. 10. Calmodulin activated, stays active even past calcium decrease and signal end.
  8. 11. When activated by cGMP causes the relaxation of blood vessel smooth muscle.
  9. 12. The ER stored second messenger that can be quickly released by the IP3-dependent channel.
  10. 13. Ca2+-binding protein with no catalytic activity that activates other proteins when bound to them.
  11. 14. Cleaves PIP2 into IP3 and DAG.
  12. 16. Monomeric G protein that is active when bound to GTP and phosphorylates Raf.
  13. 17. Protein kinase that is phosphorylated by Raf.
Down
  1. 2. Activated by DAG and intracellular calcium release.
  2. 3. Regulated by the inhibitory action of two cAMP binding proteins.
  3. 4. Activated by dimerization guided autophosphorylation of intracellular tyrosine domains.
  4. 9. Catalyzes the formation of cGMP from GTP.
  5. 15. Ras-GEF that activates Ras by exchanging GTP for GDP.