Cellular components of connective tissue

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Across
  1. 5. multipotent stem cells found in bone marrow that are important for making and repairing skeletal tissues, such as cartilage, bone and the fat found in bone marrow.
  2. 6. transport oxygen from the lungs to body tissues and transport carbon dioxide from body tissues to the lungs
  3. 9. store and release lipids for energy, insulation and as an energy reserve
  4. 10. release histamine and other mediators in response to allergens or injuries. They also contain heparin which is an anticoagulant
  5. 12. synthesise and mineralise bone matrix, collagen and hydroxyapatite
  6. 13. are part of the immune system to defend against pathogens, examples are neutrophils and basophils
  7. 14. produce antibodies as part of the adaptive immune response against pathogens
Down
  1. 1. produce and maintain the extracellular matrix of cartilage
  2. 2. these regulate bone remodelling and calcium homeostasis
  3. 3. regulate blood flow and contribute to blood vessel formation and stability
  4. 4. cells in the body's connective tissues, contributing to tissue repair, maintenance, and remodeling. Their ability to produce extracellular matrix proteins makes them essential for the structural integrity of organs and tissues throughout the body.
  5. 7. engage in the phagocytosis of pathogens and debris, antigen-presentation to lymphocytes, produce cytokines/chemokines for immune response and inflammation
  6. 8. are essential for blood clotting and wound healing
  7. 11. are specialised cells found especially in immune organs, used to provide structural support (they are stromal cells)