CH 13 Adaptive Immunity and Immunization

2. This type of lymphocyte is produced in the bone marrow but matures in the thymus
8. A subset against primarily intracellular pathogens.
9. A subset that contributes to protection at mucosal surfaces.
11. This was used in the 10th century where there was deliberate inoculation of dried pus from smallpox pustules of one patient into the arm of a healthy person
12. These modulate the immune response, including by limiting chronic inflammatory diseases
15. The type of response where the antibodies, rather than the B cells themselves, are able to bind to pathogens and mark them for elimination.
16. A subset leading to a humoral response.

1. Treatment with antibodies against a particular pathogen for immediate effect against pathogen. This is temporary and has no memory induction, meaning in order to maintain response you have to give more antibodies
3. These directly destroy cells they recognize, which are often virus infected cells
4. This develops when the innate immune system cannot handle getting rid of the pathogen and involves a very specific response to a pathogen and is slower to develop.
5. This type of lymphocyte is produced and matures in the bone marrow
6. These are "the conductors" of "the immune orchestra". They detect pathogens and activate other immune cells to fight them. They also recognize antigen presented via MHC II and expresses CD4
7. These are substances that can elicit a response from a B or T cell
10. The small accessible part of an antigen that binds to an antigen receptor
11. Any immunity obtained by inoculation with selected antigens/parts of a microbe, or the entire microbe.
13. These account for 20-40% of all leukocytes, the smallest type of WBC ,nucleus is dark and round, and contain little cytoplasm.
14. These are host proteins that display antigen fragments on the cell surface (antigen presentation)and is necessary for the T cell to participate in the adaptive immune response