CH. 17 HW

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Across
  1. 2. “Holey” brain appearance from prion damage (vacuoles/plaques).
  2. 4. Light sensitivity, a symptom of meningitis.
  3. 10. Fluid (CSF) that cushions the brain/spinal cord within bony casings.
  4. 13. Steam sterilization method, typical cycles do NOT kill prions.
  5. 15. Abnormally small head in babies caused by congenital Zika syndrome.
Down
  1. 1. infectious particle with no genetic material, causes TSEs.
  2. 3. (Cryptococcus neoformans) that rarely causes meningitis, often in AIDS patients.
  3. 5. Pertaining to lower back, lumbar puncture = spinal tap to sample CSF for diagnosis.
  4. 6. Immunoglobulin A, Neisseria meningitidis produces IgA protease as a virulence factor.
  5. 7. Protective membranes covering the brain and spinal cord, inflammation = meningitis.
  6. 8. spherical bacteria, Neisseria meningitidis appears as Gram-negative diplococci.
  7. 9. Primary Amoebic Meningoencephalitis (PAM), enters via nasal passages.
  8. 11. LPS released by Neisseria meningitidis that stimulates leukocytes and damages blood vessels.
  9. 12. Brain cells with phagocytic capability but reduced activity vs. other body parts.
  10. 14. Small red/purple spots on trunk/appendages from hemorrhage due to immune response.