Chapter_Immune response to tumors

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Across
  1. 1. downregulation of this surface protein makes tumor cells susceptible to NK cells
  2. 3. cancers of epithelial cells
  3. 6. a term that means control and elimination of malignant cells by the immune system
  4. 7. cancer of the immune system involving circulating cells
  5. 9. the branch of medicine that deals with tumors
  6. 10. tumors that are encapsulated, localized, and limited in size (no need for the word ‘tumor’)
  7. 11. uncontrolled growth of cells
  8. 13. the inhibitory receptor on T cells for B7
  9. 14. therapy using T cells expressing chimeric antigen receptors (CARs)
  10. 15. a large number of mutations present in diverse genes which play no role in tumorigenesis (no need to include the word ‘mutations’)
Down
  1. 2. tumors that stop expressing the antigens that are the targets of immune attack
  2. 4. When cluster of cancerous cells dislodge from the primary site and travel via blood or lymphatic vessels to distant tissues
  3. 5. the approach of stimulating immune responses by a drug that inhibits the inhibitors
  4. 8. cancer involving bone marrow
  5. 12. chemical produced by macrophages that helps in killing on tumor cells