Constipation- Overview

1234567891011121314151617181920
Across
  1. 2. 17g of this product needs to be mixed with H2O or juice. Also commonly used for bowel prep in colonoscopies
  2. 4. Brand name for naloxegol. MOA: Mu opioid receptor antagonist
  3. 7. Class of pain medications that commonly cause constipation
  4. 8. _____ laxatives form emollient gels that absorb water back into the stool, which push against colon walls to stimulate peristalsis. Gas formation is a common side effect
  5. 9. Constipation is defined by less than _____ bowel movements per week with signs and symptoms
  6. 11. brand name for methylcellulose
  7. 13. Brand name of lubiprostone. MOA: Activates Cl- channels to cause an influx of Na+ into the small intestine, increasing fluid movement into the intestinal lumen
  8. 14. stool softener that is not effective for active constipation
  9. 15. Brand name for Prucalopride. MOA: Activates 5-HT4 receptors which facilitates the release of ACh, resulting in enhanced colonic peristalsis
  10. 18. Poorly absorbed sugar that takes 1-3 days to stimulate a bowel movement (also used to treat hepatic encephalopathy)
  11. 20. poorly absorbed sugar that takes 1-3 days to stimulate a bowel movement
Down
  1. 1. Brand name for psyllium
  2. 3. enteric coated tablets that activate enteric nerves to induce colonic contractions; also comes in 10mg suppositories for quick onset
  3. 5. This class of laxatives include aloe, cascara, and senna. MOA: activates enteric nerves to induce colonic contractions and increases fluid and Na+ secretion into the lumen
  4. 6. recommend slowly increasing _____ into diet over 7-10 days
  5. 10. these types of agents are poorly absorbed sugars that draw water into the colon to stimulate bowel movement
  6. 12. Non-pharmacological recommendations include 6-8 glasses of _____
  7. 16. Brand name methylnaltrexone. MOA: Mu opioid receptor antagonist, stimulates BM within 30 minutes
  8. 17. Brand name for linaclotide. MOA: Guanylate cyclase C agonist that increases chloride and bicarbonate secretions into the intestinal lumen, and inhibits Na+ reabsorption
  9. 19. chronic constipation includes symptoms last more than _____ weeks