NPW 2024 - Crossword Competition

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Across
  1. 2. The process by which a drug crosses the blood-brain barrier and exerts its therapeutic effect on the central nervous system.
  2. 6. A class of drugs used to relieve pain by binding to opioid receptors in the central nervous system but without affecting consciousness.
  3. 9. The journey of a drug travelling from the site of administration to the site of action
  4. 10. This non-invasive imaging technique is often used to track drug distribution and metabolism in the body using a small radioactive substance.
  5. 12. A class of medications that bind to and inhibit specific enzymes involved in the synthesis of key neurotransmitters, often used in psychiatric treatments.
  6. 16. A drug delivery system that utilizes nanoparticles to improve the bioavailability and targeting of drugs.
  7. 21. Chemical-driven liver damage
  8. 22. A condition in which the immune system attacks its own cells, often treated by immunosuppressive drugs.
  9. 23. A type of drug that promotes the movement of bodily fluids, often used to treat conditions such as heart failure.
  10. 24. The phenomenon where certain diseases are effectively treated with the patient’s own cells, such as stem cell therapy and gene editing.
Down
  1. 1. The federal agency that plays a crucial role in regulating drug safety, conducting post-market surveillance, and ensuring the compliance of pharmaceutical companies.
  2. 3. The final step in the pharmacokinetics process, where drugs or their metabolites are expelled from the body, often via renal or biliary excretion.
  3. 4. This new class of drugs targets specific proteins responsible for cancer cell growth, often used as targeted therapies in oncology.
  4. 5. A term used to describe the amount of drug that reaches systemic circulation and is available to exert therapeutic effects.
  5. 6. A type of disease that is characterized by a rapid onset and short duration, often requiring immediate medical intervention.
  6. 7. This term refers to a phenomenon where a drug's effect becomes weaker or less effective over time with continued use, often requiring dose adjustments.
  7. 8. A substance that prevents or counteracts the effects of toxins or poisons, often used in cases of overdose.
  8. 11. This term refers to the variability in drug responses between different individuals due to genetic factors.
  9. 13. A medical condition where the heart’s pumping ability is compromised, often requiring both pharmaceutical and non-pharmaceutical interventions.
  10. 14. The phenomenon in which the presence of one drug increases the effect of another, often leading to toxicities or adverse reactions.
  11. 15. This pharmaceutical formulation uses a combination of active and inactive ingredients to ensure controlled delivery of the drug over a prolonged period.
  12. 17. A therapeutic strategy that uses the body's immune system to fight diseases like cancer, often involving monoclonal antibodies.
  13. 18. This term refers to the ability of a drug to block the activity of enzymes or receptors, thus reducing or preventing the progression of disease.
  14. 19. Single-celled microorganisms studied in pharmaceutical microbiology, some of which have evolved resistance to multiple antibiotics, complicating treatment options.
  15. 20. A class of drugs that selectively binds to and activates specific receptors in the brain to manage anxiety and panic disorders.