CROSSWORD PUZZLE

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Across
  1. 4. The SMOC1 domain crucial for binding to thrombin
  2. 6. Increased platelet response observed in diabetes
  3. 9. Cell fragments responsible for forming clots
  4. 12. Removal of a gene to study its function
  5. 14. Whose function is decreased by thrombin in endothelial cells
  6. 15. Post-translational modification observed in β3 integrin upon increase in SMOC1
  7. 16. MicroRNA that regulates SMOC1 expression
Down
  1. 1. General process of turning platelets “on”
  2. 2. Process where platelets stick together
  3. 3. Ion that increases during platelet activation
  4. 5. Molecule used to block SMOC1 in the study
  5. 7. Disease associated with increased clotting risk
  6. 8. Protein identified in the study that enhances thrombin activity
  7. 10. Cell surface receptor involved in platelet adhesion
  8. 11. Formation of a blood clot inside a vessel
  9. 13. Enzyme that activates platelets during clotting