d103

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Across
  1. 4. Broad sheet-like actin protrusion at the leading edge that drives forward movement during migration
  2. 5. Calcium-dependent cell-cell adhesion molecule that links neighboring cells to actin and distributes lateral tension across tissues
  3. 7. Actin-based motor protein that generates contractile force during trailing edge retraction
  4. 8. Small GTPase that promotes stress fiber formation and myosin-mediated contraction at the rear of migrating cells
  5. 9. Transmembrane receptor that connects the extracellular matrix to the cytoskeleton and mediates cell-ECM adhesion
Down
  1. 1. Cell-ECM junctions that anchor intermediate filaments to the basement membrane
  2. 2. Thin finger-like actin projections that sense environmental cues and guide directional movement
  3. 3. Small GTPase that promotes branched actin polymerization and lamellipodia formation at the front of migrating cells
  4. 6. Intermediate filament protein in epithelial cells that provides tensile strength and is commonly mutated in epidermolysis bullosa