D1.3 Mutation and Gene Editing Crossword Puzzle

1234567891011121314
Across
  1. 2. _______ mutations can cause diseases, developmental abnormalities, or reduce the organism's fitness and survival.
  2. 4. ________ mutations are rare but can provide advantages to an organism and increase its fitness in a particular environment.
  3. 6. ______ sequences are those that remain identical or similar across a species or group of species.
  4. 7. Bacteria employ the _____ as a means of self-defence against invading foreign DNA, such as viruses.
  5. 9. Mustard gas and nitrous acid are types of ____ Mutagens.
  6. 11. _____ mutations are those that do not significantly affect the organism.
  7. 13. ______ is the molecule is designed to target and bind to a particular DNA sequence of interest
  8. 14. ____ occur when one nucleotide is replaced by another nucleotide in the DNA sequence.
Down
  1. 1. A type of substitutions that are known as neutral mutations as they do not change the amino acid sequence due to the degeneracy of the genetic code.
  2. 3. ______ are agents that can cause mutations.
  3. 5. Mutations in ____ can be passed onto offspring and affect their traits.
  4. 8. _____ is an enzyme that locates a specific DNA sequence and enables sgRNA to make precise cuts in the DNA resulting in a double-strand break.
  5. 10. _____ is a technique in which a specific gene is intentionally made inoperative to study its function.
  6. 12. ______ mutations can be caused by insertions or deletions, which alter the reading frame of codons.