Discuss the basic epidemiology, pathophysiology, presentation, investigation, management and prognosis of osteoarthritis

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Across
  1. 4. muscles surrounding the joints often waste away
  2. 7. joint ----------- surgery is the best long term outcome
  3. 9. caused by a predisposing condition
  4. 12. proximal interphalangeal joint
  5. 13. this scan would be done if suspect associated soft tissue injury
Down
  1. 1. the natural wear and tear of the joints
  2. 2. the matrix becomes unstable due to the loss of -------
  3. 3. to relieve symptoms of pain
  4. 5. --------- of the cartilage occurs and this leads to the development of chronrocyte death
  5. 6. cysts the bone hardens and develops
  6. 8. aspiration of the synovial fluid would be ------- and have a low cell count
  7. 10. distal interphalangeal joint of hand
  8. 11. it is the degeneration of articular cartilage and its disordered repair