Energy and Enzymes

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Across
  1. 4. ideal conditions for a specific enzyme to function
  2. 8. term that describes the slowing down of an enzyme-catalyzed reaction as substrate concentration increases
  3. 9. typically a mineral that reversibly interacts with and is essential for enzyme function
  4. 13. term for the items that go into a chemical reaction
  5. 15. includes factors that affect the rate of an enzyme-catalyzed reaction such as temperature, pH, and substrate concentration
  6. 19. state where substrate bonds are partially formed or broken down, involving changes in the shape of the enzyme
  7. 20. term that describes the specificity of the shape and charge of the substrate binding domain for a specific substrate
  8. 22. a reaction where the reactants and products have the same free energy (deltaG=0)
  9. 25. site in an enzyme where the substrate(s) binds
  10. 26. a reaction that requires heat to occur
  11. 27. molecules that enzymes work on
  12. 29. primary sequence of amino acids
  13. 31. degree of disorder in a system
Down
  1. 1. disruption in the genetic code that may ultimately affect enzyme structure and function
  2. 2. type of regulation where the regulatory molecule binds outside of the active site causing shape changes that can activate or inhibit the enzyme
  3. 3. type of inhibition where a product of a metabolic pathway binds to, and inhibits, an enzyme that functions early in the pathway
  4. 5. type of inhibition where the inhibitor competes with the substrate(s) for an enzyme’s binding site
  5. 6. step of enzyme catalysis where substrates bind the enzyme
  6. 7. component that facilitates a reaction but is unchanged by the reaction
  7. 10. type of energy required to reach the transition state
  8. 11. stored energy
  9. 12. a reaction that is not energetically favorable (deltaG>0)
  10. 14. a reaction where the reactants have higher free energy than the products
  11. 16. a reaction that releases heat
  12. 17. step of enzyme catalysis where products are discharged from the enzyme
  13. 18. non-amino groups that covalently attach to enzymes, altering their function
  14. 21. all of the things that are produced by a reaction
  15. 23. term for free energy that takes into account entropy, enthalpy and temperature
  16. 24. a favorable, spontaneous reaction (deltaG<0)
  17. 26. internal energy of a system including heat, pressure and volume
  18. 28. molecules that shuttle electrons and reversibly interact with an enzyme to enhance its function; often vitamins or their derivatives
  19. 30. typically a protein that facilitates a chemical reaction by bringing substrates together