Enzyme crossword

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Across
  1. 2. Reduce or stop the enzyme from functioning
  2. 5. A reaction that has a net release of free energy
  3. 7. A reaction that absorbs free energy from the surroundings
  4. 10. The process of breaking down large molecules into smaller ones
  5. 11. An organic cofactor such as vitamins and NAD+
  6. 12. The substances used up or changed during the reaction
Down
  1. 1. The model where the active site is flexible and can change shape to conform to the substrate
  2. 3. The model where the active site of an enzyme has a set shape
  3. 4. The energy required to start a reaction
  4. 6. The sum of all the chemical reactions occuring in that cell.
  5. 8. The substances produced as a result of a reaction
  6. 9. The process of making large molecules from smaller ones