exam 2

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Across
  1. 2. Proteins that have many different variants across the human population are called
  2. 3. Naïve T cells can be induced to become regulatory T cells through exposure to:
  3. 6. The broad concept of by which our B and T cells “learn” to not react to our own bodies is called
  4. 10. Peptides fragments in the cytoplasm of human cells are taken to the endoplasmic reticulum by:
  5. 11. Proteins displayed on class I MHC molecules are
  6. 12. Peyer’s Patches are located in this tissue
  7. 13. What kind of cell serves as the mechanism for getting antigen into the Peyer’s patch?
  8. 14. Both B and T cells begin life in the:
  9. 15. Follicular dendritic cells use what molecule to attract B cells so the B cells may “sample” their antigens?
  10. 17. The portion of the invariant chain that occupies the class II MHC groove in an endosome is called
  11. 18. IL-12 is a cytokine that causes uncommitted T helper cells to become what class of T helper cell?
  12. 19. Activated T cells have license to visit specific areas of the body, and their ability to visit a site (or to not visit a site) is controlled by
Down
  1. 1. What kinds of cells inspect the peptides presented on class I MHC molecules
  2. 4. The secondary lymphoid structure with the job of presenting opsonized antigens to B cells is
  3. 5. Virgin B cells that don’t pass the first test of having produced antibodies that do not react to self are given a second chance to change their light chain genes to create a new receptor in a process called
  4. 7. The component produced by CTLs that punches a hole into an infected cell’s membrane is called
  5. 8. MHC restriction is also known as:
  6. 9. IL-4 is a cytokine that causes uncommitted T helper cells to become what class of T helper cell?
  7. 16. The structures which can best be described as a sea of B cells that contain islands of follicular dendritic cells are called
  8. 17. helper T cells use ________ as the co-receptor.