Fatty acid oxidation

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Across
  1. 4. Fatty acids transported on what protein in plasma
  2. 5. Fatty acids normally have an odd number of carbon atoms.True or False?
  3. 6. What must long chain acyl-CoA units form in order to penetrate the inner mitochondrial membrane?
  4. 9. Enzymatic deficiency in alpha-oxidation leads to _____________ disease
  5. 12. Activation of fatty acid occurs here
  6. 14. dehydrogenase, Generates NADH while oxidating hydroxylacyl CoA
  7. 16. Where are fatty acids degraded?
  8. 17. oxidases, What type of enzymes catalyze beta-oxidation of fatty acid?
  9. 18. acyl-CoA, Reformed in the mitochondrial matrix with the release of carnitine
  10. 19. Palmitic acid requires ______ cycles of mitochondrial beta-oxidation
  11. 21. Degradation of odd number fatty acids produces __________
  12. 24. The conversion of long chin fatty acid to fatty acyl CoA requires___________
  13. 25. What shuttles the CoA through the inner membrane of mitochondria?
  14. 26. Naturally occuring fatty acids usually assume the _______ configuration
Down
  1. 1. Fatty acid activation releases this and AMP
  2. 2. How many molecules of acetyl-CoA will be created from a 14 carbon fatty acid?
  3. 3. isomerase, This enzyme rearranges cis to trans in beta-oxidation of unsaturated fatty acids
  4. 7. Major regulation of beta-oxidation involves hormone ________
  5. 8. Fatty acids are synthesized from and oxidized to this compound
  6. 10. Oxidation of palmitic acid yields _______ molecules of acetyl-CoA
  7. 11. Enzyme catalyzing the final step of beta oxidation
  8. 12. acyltranferase, Facilitates transport of acetyl groups through mitochondrial membrane
  9. 13. Propionyl-CoA enter the Krebs cycle through __________
  10. 15. acids, W-oxidation produces ___________
  11. 20. peroxide, Mixed oxidase enzyme produce ___________ as byproduct
  12. 21. Degradation of very long chain fatty acids (>22 carbon) occurs in ________
  13. 22. acid, Accumulation of ___________ in alpha oxidation leads to neurological damage
  14. 23. Each cycle of beta oxidation produces ________ FADH2, NADH and acetyl-CoA