GENE CHECKERS

1234567891011121314151617181920212223242526272829
Across
  1. 4. Chromatin involved in active transcription of DNA to mRNA products.
  2. 5. processes involving the transfer of naked fragments of DNA between bacteria
  3. 6. First human chromosome to be sequenced as part of the Human Genome Project
  4. 8. Determining the order of the four nucleotide bases in a DNA strand
  5. 9. Sequencing technique which uses chain terminating dideoxynucleotides
  6. 13. Syndrome indicated by the presence of an extra barr body in the embryo during amniocentesis
  7. 14. The unit for measuring genetic linkage was named after (2 words)
  8. 15. Tendency of two or more genes to stay together during inheritance
  9. 16. Discoverer of the rules of complementary base pairing.
  10. 21. Mutation which does not change the function of a protein despite a change in the sequence of nucleotide bases.
  11. 22. H1 histone binding to a nucleosome form:
  12. 25. Transplantation of normal genes into cells as replacement for missing or defective genes (2 words).
  13. 26. Chromosome segment is reversed end to end in this type of mutation.
  14. 27. Cloning vector that contains the necessary prokaryotic promoter before a restriction site where a eukaryotic gene can be inserted (2 words).
  15. 29. A virus outbreak during which the Convalescent,Plasma Therapy was used, other than the Covid-19 virus.
Down
  1. 1. Unexpected expression of a recessive trait caused by the absence of a dominant allele
  2. 2. One of the stages of Prophase 1, wherein homologous chromosomes pair to form bivalents.
  3. 3. The genomic process of gene silencing through DNA methylation
  4. 7. Short single stranded DNA fragments synthesized during DNA replication and covalently joined to make continuous strands
  5. 10. Random change in allelic frequency due to chance (2 words)
  6. 11. One of the Nobel laureates for development of genome editing tool (2 words)
  7. 12. DNA made from an RNA template catalysed by reverse transcriptase (Abbreviation)
  8. 17. Pedigree relationships between groups of cells.
  9. 18. A unit made up of linked genes that code for proteins required for a specific task
  10. 19. Study of heritable changes in gene expression which occur without any changes to the gene sequence.
  11. 20. Syndrome caused by trisomy of chromosome 13.
  12. 22. An Indian Covid-19 vaccine
  13. 23. First drug approved by FDA for treatment of SARS-CoV 2 Virus.
  14. 24. New genetic material is generated during molecular evolution through this mechanism
  15. 28. Protein encoded by the longest gene found in the human genome.