Gene mutation and sickle cell anaemia

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Across
  1. 5. The cellular organelle synthesizes proteins
  2. 7. A type of mutation where one base pair is replaced by another.
  3. 8. The organ that is most affected by sickle cell disease.
  4. 11. The type of inheritance pattern sickle cell anemia follows.
  5. 14. The chromosome that carries HBB gene.
  6. 15. The type of mutation that changes one nucleotide in DNA.
  7. 17. The shape of red blood cells in sickle cell anemia.
  8. 18. The gene that codes for the affected protein in sickle cell anemia.
  9. 19. The amino acid replaces glutamic acid in sickle cell anemia
  10. 20. The base that replaces adenine in the mutated gene causing sickle cell anemia
Down
  1. 1. The condition results from blocked blood flow due to sickle cells.
  2. 2. The protein affected by sickle cell mutation.
  3. 3. The molecule carries the genetic code from DNA to ribosomes
  4. 4. The specific amino acid that is changed in sickle cell anaemia
  5. 6. The type of hemoglobin produced due to this mutation
  6. 9. The main symptom of sickle cell disease caused by blocked blood flow.
  7. 10. The type of mutation involves the addition or deletion of nucleotides
  8. 12. The hormone that stimulates red blood cell production
  9. 13. The process that creates different versions of a gene
  10. 16. The type of mutation in sickle cell disease, affecting a single nucleotide.