General Pharmacology

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Across
  1. 5. Study of drug movement through the body.
  2. 7. tolerance Reduced effect of drug over time.
  3. 8. Maximum effect a drug can produce.
  4. 9. Amount of drug needed for effect.
  5. 12. of distribution Hypothetical space drug occupies in the body.
  6. 13. dose Large initial dose to quickly reach therapeutic level.
  7. 15. Drug that blocks receptors.
  8. 16. Rapid decrease in drug response.
  9. 20. reaction Unpredictable, unusual drug reaction.
  10. 21. Biochemical alteration of drugs in the liver.
  11. 22. Constant drug concentration in the bloodstream.
  12. 25. Drug that activates receptors.
  13. 26. dose Dose to maintain drug level within therapeutic range.
  14. 28. effect Drug metabolism in liver before reaching circulation.
  15. 29. inhibition Decrease in enzyme activity, increasing drug levels.
Down
  1. 1. Study of genetic influence on drug response.
  2. 2. Study of drug effects on the body.
  3. 3. Dispersion of drug throughout the body.
  4. 4. Fraction of administered drug that reaches systemic circulation.
  5. 6. window Range between effective and toxic dose.
  6. 10. protein binding Drug binding to albumin affecting distribution.
  7. 11. Time for drug concentration to reduce by half.
  8. 14. index Ratio of toxic dose to effective dose.
  9. 15. Movement of drug from site of administration to bloodstream.
  10. 17. Strength of binding between drug and receptor.
  11. 18. Inactive compound converted to active form in body.
  12. 19. induction Increase in enzyme activity, reducing drug levels.
  13. 23. effect Harmful reaction to a drug.
  14. 24. Removal of drugs from the body, mainly by kidneys.
  15. 27. effect Unintended effect of a drug at therapeutic dose.