GENERAL PHARMACOLOGY CROSSWORD

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Across
  1. 4. Sulphonamides bind to this plasma protein
  2. 6. Science related to detection, understanding and prevention of ADR
  3. 10. Large scale manufacture of drugs
  4. 11. Genetically determined abnormal reactivity to a chemical
  5. 14. Most important mechanism of transport of drugs across membranes
  6. 16. Ethyl alcohol follows this order of elimination kinetics
  7. 17. "drug" is derived from this French word meaning dry herb
Down
  1. 1. Father of Pharmacology
  2. 2. Antagonism between Ach and Atropine
  3. 3. Inactivation of the drug in body fluids by molecular rearrangement without agency of enzyme
  4. 5. Rapid development of tolerance on repeated administration of drug
  5. 6. Inert substance given to treat patient psychodynamically
  6. 7. Digoxin is this type of inhibitor
  7. 8. Sulphonamide is conjugated by
  8. 9. Breakdown of GTP to GDP is action of this subunit of G-protein
  9. 12. Theoretical volume of plasma from which the drug is removed completely in unit time
  10. 13. When action of one drug is facilitated by another
  11. 15. Drug required for treatment or prevention of a rare disease